Situated approximately 5 minutes' walk from the Ottoman imperial Pertevniyal Valide Sultan Mosque, Hotel Fortynine Istanbul includes 16 rooms with views of the city.

This Istanbul hotel is 2.1 km from the Galata Bridge, while the TGC Press Media Museum is just 1.9 km away. The hotel offers proximity to natural sights like the historical urban Gulhane Park (2.4 km) and Miniaturk Miniature Park (6 km). The neoclassical Istanbul Archaeology Museums lies nearly 10 minutes' drive away, while Aksaray tube station is right around the corner from the Fortynine. The property is also 650 m from Yenikapi train station, and 45 minutes' driving distance from Istanbul Sabiha Gokcen International airport.

The rooms at the hotel include air conditioning, as well as media facilities like a flat-screen TV with satellite channels. A separate toilet and a shower, along with hair dryers and bath sheets, are featured.

While staying at Hotel Fortynine, guests can choose from dining options nearby, such as Byzantion Bistro & Restaurant, located a mere 7 minutes' walk away, or Pacaci Hasan at a 7-minute walking distance.