Nestled in Golden Horn, which is a natural harbour off the strait, Frame Hotel & Suites Istanbul is just 1.5 km from the 400-year-old New Mosque.

Located nearly 20 minutes' walk from the Ottoman imperial Suleymaniye Mosque, this Istanbul hotel is also nearly 20 minutes' walk from Sirkeci railway station. As a plus for business travellers, the 85m-tall Beyazit Tower is 2.3 km away. The Taksim Gezi Park lies about a 10-minute ride away, while Sishane tube station is in the immediate vicinity of the Frame Hotel & Suites Istanbul. The hotel stands close to Istanbul Riverside Museum of Modern Art, a mere 350 metres from Kemeralti bus stop.

There are 7 rooms comprising a sitting area and a dining area. They come with a television with satellite channels, as well as such comforts as an iron with ironing board and climate control. They are furnished with sound-proof windows, and also come with a minibar fridge and coffee/tea making facilities. The bathrooms feature a separate toilet and a shower, along with a hair dryer and bath sheets.

While staying at Frame Hotel & Suites, guests can choose from dining options nearby, such as Cafe Privato, located approximately a 5-minute walk away, or Galata Frida House Cafe at a 5-minute walking distance.