Guests of Isle Hotel Istanbul can enjoy access to the historical urban Gulhane Park, located 25 minutes' walk away.

Istanbul Riverside Museum of Modern Art is around 300 metres away, while Sirkeci train station is a mere 1.7 km from this hotel. The Bulgarian Orthodox Church lies 30 minutes' walk from the 4-star hotel. The Isle is also within a few blocks of the great Hagia Sophia Museum and Karakoey bus station is 0.9 km away. Sishane underground station is at a distance of 350 metres from this property.

The restaurant 360 Istanbul is a 6-minute stroll away.