Offering a restaurant and luggage storage, the comfortable 3-star Hotel Kayisi Istanbul lies in Laleli, which is known by some as Istanbul's Russia Town, just 200 metres from Haci Bayram Kaftani Cami and about a 10-minute drive from such cultural places of interest as the large Topkapi Palace harem Museum. Right around the corner from the Ottoman imperial Pertevniyal Valide Sultan Mosque, this Istanbul hotel with 17 rooms features currency exchange and a lift.

Located within 25 minutes' walk of the Ottoman-era Friday Blue Mosque, the hotel is also within 10 minutes' walk of Yenikapi railway station. The Kayisi Istanbul is just 450 metres from Cambaziye Cami, and Cagaloglu Hamami Public Bath, where guests can indulge in relaxation, stands 2.3 km away. Panorama 1453 History Museum lies approximately a 15-minute ride away, and Aksaray tube station is in close proximity to the accommodation. This Istanbul hotel is within a 400-metre distance of IETT Aksaray Peron Duragi bus station.

The air-conditioned rooms in Hotel Kayisi have Wi-Fi and a flat-screen TV with satellite channels along with air conditioning and soundproof walls. There is also a private bathroom. Guests can make use of a hair dryer and towels in the bathrooms equipped with a separate toilet and a shower.

The Kayisi has an à la carte restaurant, serving a range of halal dishes. At Byzantion Bistro & Restaurant, situated just around the corner from the property, you can taste healthy cuisine.