Located only 400 metres from the Prepuets Eyt, Marcello Hotel Istanbul is a mere 5 minutes' walk from the prominent Turkish Istanbul University. Wi-Fi is provided in public areas, as well as currency exchange and a lift are available on site too.

The hotel is centrally situated about 3 km from the byzantine monument "Kariye Mosque". The large Topkapi Palace harem Museum is right near the Marcello Istanbul, while Laleli bus stop is approximately 5 minutes' walk away. This 3-star hotel is also within reach of Gulhane Park. The nearby shopping sights include the historic Sultanahmet District, which is 2.1 km away. The property is a 46-minute drive from Istanbul Sabiha Gokcen International airport, and in proximity to Yenikapi train station.

Marcello Hotel has 43 rooms with a dining area. A flat-screen TV with satellite channels along with a minibar fridge and tea/coffee making equipment are provided. An iron and ironing board, and air conditioning are featured for guests' comfort. Bathroom essentials include a separate toilet and a shower, and such comforts as a hair dryer and bath sheets.

The hotel serves a free buffet breakfast. There is a terrace bar onsite. The bar area includes a terrace and a lounge. Located 12 minutes' stroll from the Marcello, the seafood restaurant ANTAKYA Restaurant offers a Middle Eastern menu.