Located around 600 metres from the large Topkapi Palace harem Museum, Merih 2 Hotel Istanbul is just 6 minutes' walk from Istanbul Museum of the History of Science and Technology in Islam.

Blue Mosque is only 650 metres away, while Sirkeci train station is fairly close to the hotel. A popular place in Istanbul is Eminonu Pier, which is merely 9 minutes' walk away. This Istanbul hotel is situated a mere 1.6 km from Galata Bridge, and Havatas transfer bus station lies a mere 0.8 km away.

The accommodation is near Mom's Corner serving Turkish dishes.