Located in close proximity to the 18th-century Ottoman Nuruosmaniye Mosque, the 4-star smoke-free Orient Occident Hotel Istanbul, Autograph Collection provides guests with 24-hour reception and wake-up calls. Featuring a restaurant, this Istanbul hotel is around a 5-minute drive from the Boukoleon Palace.

The centre of Istanbul can be reached within a 10-minute walk, and natural attractions like the Taksim Gezi Park are approximately 3 km away. The Orient Occident Hotel Istanbul, Autograph Collection is only 10 minutes' stroll from Big Tours Istanbul bus stop and only steps away from Cagaloglu Hamami Public Bath. Also, Istanbul Riverside Museum of Modern Art lies 2.2 km away, and Vezneciler-İstanbul Üniversitesi underground station is 950 m from the hotel. The accommodation is located in Istanbul, in proximity to Sirkeci train station.

The rooms at Orient Occident Hotel Istanbul, Autograph Collection are fitted with an iron and climate control as well as a minibar fridge, coffee and tea making facilities. Furnished with a writing desk, they also have sound-proofed windows. Bathrooms come with a walk-in shower and a separate toilet, along with shower caps and towels. Guests can enjoy views of the city.

The à la carte restaurant in the Orient Occident Hotel Istanbul, Autograph Collection offers dishes for lunch. The restaurant serves European cuisine. There is also a coffee bar. The bar area includes a lounge and a terrace. While staying at this Istanbul hotel, guests can choose from dining options nearby, such as Bitlisli, located nearly a 5-minute stroll away, or Mavi Bufe at a 5-minute walking distance.