Santa Rio Taxim Hotel Istanbul is conveniently located 6 minutes' walk from the cobblestone Istiklal Street and offers views of the garden. Offering a 24-hour front desk and wake-up calls, this hotel also features Wi-Fi in the rooms.

The national Maritime Museum is in the vicinity of the 4-star hotel and the Beyoglu is 1.3 km away. The Santa Rio Taxim is 11 minutes' stroll from Clinicana Hair Transplant and Esthetic Surgeries and 45 km from Istanbul airport. This property is 3.4 km from the Basilica Cistern. The hotel is 450 metres from Hava Airport bus stop and within reach of Taksim underground station.

The accommodation offers rooms with an adjoining terrace and a dining area featuring ironing facilities and climate control, along with high-speed internet and a flat-screen TV with satellite channels. Furnished with a writing desk, they also have soundproof windows. Extra-long beds with non-allergenic pillows as well as electric blankets are also available. Bathrooms include a separate toilet and a shower, and such comforts as a hairdryer and toiletries.

Located 5 minutes on foot from Santa Rio Taxim Hotel, the restaurant Zubeyir Ocakbasi offers a Turkish menu.