Sis Hotel Istanbul, located 25 minutes' walk from the Basilica Cistern, features Wi-Fi in public areas. Along with a safe deposit box and 24-hour security, a lift and a vending machine may be found at this hotel.

The hotel lies in Laleli, which is known by some as Istanbul's Russia Town in the immediate vicinity of the Ottoman imperial Pertevniyal Valide Sultan Mosque. The Sis in Istanbul is 2.3 km from the functioning Blue Mosque. The ancient Sultanahmet District is a 30-minute walk away. This property is 750 metres from Yusufpasa bus stop and in proximity to Aksaray underground station.

Furnished with a writing desk, the 18 rooms also include such conveniences as a flat-screen TV with satellite channels, along with a mini fridge bar, coffee and tea making equipment. Air conditioning are featured for guests' comfort. Bathrooms are fitted with a bidet, a separate toilet, and a shower as well as shower caps and towels.

A free breakfast is served in Sis Hotel daily. The seafood restaurant Messo Restaurant is a 5-minute stroll away.