Offering a shared lounge and various recreational opportunities, as well as the views of the garden, the 3-star smoke-free The 22 Hotel Istanbul is located about 25 minutes' walk from the American Hospital. Boasting a location in close proximity to the Istanbul Cevahir Shopping and Entertainment Center, the comfortable hotel offers 9 rooms and a lounge bar onsite.

This hotel lies in the centre of Istanbul, in European Side with Istanbul's old center, with classic sights like opulent Topkapı Palace, the Blue Mosque, and Hagia Sophia, a mosque famed for its Byzantine mosaics, 350 metres from the Ataturk Museum. Within 30 minutes' walk of the fantastic 22, guests will find the national Maritime Museum. Also, Chill Pilates is situated approximately 300 metres away. There is the ornate 16th - century Suleymaniye Mosque nearly 15 minutes away by car, while Sisli Enduestri Meslek Lisesi bus station is in proximity to this accommodation. The 22 Hotel stands only 550 m from Osmanbey tube station and around 6 km from Sirkeci train station.

The soundproofed rooms feature a balcony complete with air conditioning, as well as wireless internet and a flat-screen TV with satellite channels. Furnished with soundproof windows, these air-conditioned rooms also have a writing table. Bathrooms come with a separate toilet and shower/tub combinations, along with a hair dryer and bath sheets.

A complimentary breakfast is served daily at the 22 Istanbul. There is a restaurant serving European food 5 minutes' walk away.