Located 3.4 km from the baroque Ortakoy Mosque, Tryp Istanbul Sisli Hotel is merely a 5-minute walk from the Astoria AVM. This hotel provides a safe deposit box to ensure guests' safety.

The hotel is situated in the Bomonti district, right near the restaurant Green Salads. The Ataturk Museum is just moments from the property, while Sisli Camii bus stop is around 300 metres away. The great Hagia Sophia Museum is 6 km away, while Sisli underground station is within 10 minutes' walk of the Tryp Istanbul Sisli. This hotel is a 41-minute drive from Istanbul airport, and within 8 km of Sirkeci train station.

Furnished with a writing table, the 115 rooms also include such conveniences as free wireless internet and a tv set with satellite channels, along with a mini fridge bar, tea and coffee making facilities. A rollaway bed, ironing equipment, and climate control are featured for guests' comfort. Bathrooms are fitted with a separate toilet and a shower as well as a hairdryer and slippers.