Overlooking Basilica Cistern, the smoke-free Pio Apart Hotel Istanbul is located a mere 5 minutes' stroll from the Corlulu Alipasa Madresesi and provides guests with shuttle service. This Istanbul hotel is in the Bulvarnoe Ring district, only 1.7 km from such natural sights as the historical urban Gulhane Park.

The hotel is situated approximately 20 minutes on foot from the neoclassical Istanbul Archaeology Museums and a short way from the transplanted ancient Egyptian Obelisk of Theodosius. Featuring the best options for rejuvenation, Cagaloglu Hamami Public Bath lies only 1.2 km from the Pio Apart Istanbul. The Eminönü Pier, a well-known local spot, is also a stone's throw from the accommodation. Guests will find themselves 950 m from Vezneciler-İstanbul Üniversitesi tube station, while nearly a 10-minute drive from the Ottoman-era Friday Blue Mosque.

The rooms at the Pio Apart are allergy-friendly and fitted with a flat-screen TV with satellite channels as well as coffee/tea making machines. They come with private bathrooms. Providing a separate toilet and a shower, the bathrooms are also appointed with hair dryers and complimentary toiletries. Guests can enjoy views of the city.

The neighbourhood features restaurants, including ANTAKYA Restaurant, which is in close proximity to the Pio Apart Istanbul.